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System comprises four plasma proteins, circulating as zymogens in the bloodstream or being assembled on various cell types: the serine proteases factor XII (FXII), factor XI (FXI), and prekallikrein (PKK) and the nonenzymatic cofactor high-molecularweight kininogen (HK). The latter forms equimolar complexes with plasma kallikrein (PK) or FXI. The cascade is initiated upon contact to a negatively c

M the infectious diseases working party of the German Society of Hematology and Oncology [10] for the management of sepsis in neutropenic patient recommend the use of norepinephrine as the drug of choice if a sufficient mean arterial pressure (> 65 mmHg) cannot be achieved by fluid resuscitation, associated with dobutamine in case of sepsis-related myocardial depression . Moreover, D. Schnell and

On/collection or septic shock become evident in the later course.Vasopressor regimen during septic shockThe intestinal tract is a common site of infection in neutropenic patients. Neutropenic enterocolitis, also known as typhlitis is a life-threatening condition due to inflammatory/hemorrhagic/necrotizing involvement of the lower intestinal tract [50]. Criteria for neutropenic enterocolitis associ

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