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To mediate ADCC in vitro [9, 17, 23]. Although the contribution of ADCC activity to clinical efficacy is unclear, it is important to characterize all activities of the candidate mAb, especially those that can be affected by differences in post-translational modifications, such as glycosylation. The ability of ABP 501 to induce ADCC was assessed using MT-3 cells as target cells, and NK-92M1 cells s

To mediate ADCC in vitro [9, 17, 23]. Although the contribution of ADCC activity to clinical efficacy is unclear, it is important to characterize all activities of the candidate mAb, especially those that can be affected by differences in post-translational modifications, such as glycosylation. The ability of ABP 501 to induce ADCC was assessed using MT-3 cells as target cells, and NK-92M1 cells s

Ided direct evidence that CdsF represents the chlamydial needle protein (8) while biophysical (33) and protein interaction (49) studies suggest that CT584 may be the tip protein. The composition of translocation pores remains incompletely explored. C. trachomatis CopB (CT578) has been proposed as a logical possibility since it is secreted by a type III mechanism, is detected in the inclusion membr

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